pentobarbital will minimize the level or effect of imatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
pentobarbital will minimize the level or effect of dapsone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
With therapeutic doses of TCAs, barbiturates raise metabolism and decrease blood concentrations of TCAs.
pentobarbital will lessen the extent or impact of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers can lead to reduced serum concentrations and lack of antimalarial efficacy
If this drug is used in the course of pregnancy, or In the event the patient results in being pregnant even though having this drug, the client must be apprised of the potential hazard to the fetus
Check Intently (one)pentobarbital will decrease the level or impact of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers haven't been researched, coadministration not suggested by producer
pentobarbital will reduce the level or outcome of quinidine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lower the level or outcome of eplerenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.
pentobarbital will lessen the extent or outcome of ritonavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
buprenorphine transdermal and pentobarbital both of those boost sedation. Stay clear of or Use Alternate Drug. Limit use to clients for whom alternative treatment method options are inadequate
fentanyl transmucosal and pentobarbital the two enhance sedation. Avoid or Use Alternate Drug. Limit use to people for whom substitute remedy selections are inadequate
Following stopping a CYP3A4 inducer, as being the effects more info of the inducer decline, the fentanyl plasma focus will enhance which could increase or lengthen both of those the therapeutic and adverse effects.
With therapeutic doses of TCAs, barbiturates boost metabolism and reduce blood concentrations of TCAs.
pentobarbital will decrease the extent or effect of nitrendipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.